In this latest episode, we tackle the family of protein molecules called cytokines that can have a yin and yang effect on the tumour microenvironment in many solid tumours.

Computer Graphic of TGFβ   Credit: Dr Michael Sporn, NCI

What are they and can we manipulate them and modulate their signal so as to tip things in a more positive direction in people with cancer?

Examples of cytokines include the interleukin (IL) family, interferon gamma (IFN𝛄), and transforming growth factor beta (TGFβ).