Welcome back to Season 4! This episode of Novel Targets was recorded at the 2018 annual meeting of the American Association for Cancer Research (AACR) in Chicago. This time around, we’re talking about cancer immunotherapy clinical practice, pitfalls in trial design/interpretation, emerging biomarkers, and possibilities for future cures in some patients.

Professor Tom Powles

Tom Powles (Barts Cancer Centre) is a regular on the podcast. He previously featured in Episode 7 , where he talked about some of his experience with the checkpoint inhibitor, atezolizumab, in bladder cancer.

This episode comes from ASCO 2016 in Chicago, the annual meeting of the American Society of Clinical Oncology. In it, you’ll hear experts such as Dr Johanna Bendell, Dr Jérôme Galon, and Dr Stephen Liu talk about some of the latest cancer immunotherapy data.


Dr Jérôme Galon ASCO 2016

Dr Jérôme Galon presenting Immunoscore data at ASCO 2016


One of the ASCO presentations featured in this podcast episode was by Dr Jérôme Galon (INSERM), who presented the results of a global clinical trial that validated Immunoscore as a prognostic marker in Stage I/II/III colon cancer (ASCO 2016 abstract #3500).

Lung cancer is the No 1 cause of cancer related death in the United States.

Which is why the whole of this episode is devoted to the latest lung cancer data presented at the 2015 annual meeting of the American Society of Clinical Oncology (ASCO) that took place recently in Chicago.

Photo by © ASCO/Todd Buchanan 2015

In the podcast you’ll hear from Dr Jack West (pictured right) a medical oncologist who at the time of recording was at Swedish Medical Center in Seattle (In 2019, Dr West moved to City of Hope in Duarte, California) and Dr Ross Camidge, Director of Thoracic Oncology at the University of Colorado.